Yohimbine administration and cue-reactivity in cocaine-dependent individuals
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چکیده
منابع مشابه
A preliminary report on the use of virtual reality technology to elicit craving and cue reactivity in cocaine dependent individuals.
In the present feasibility study, we developed a 3-dimensional virtual "crack" cocaine environment and evaluated the environment's ability to elicit subjective craving and cue reactivity (i.e., subjective emotional responding, heart rate and skin conductance) in 11 crack cocaine dependent individuals. Each of the seven 3-D crack cocaine scenes in the cocaine environment depicted actors engaging...
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Eighty-one cocaine-dependent outpatients were assessed for their reactions to cocaine-related cues in a laboratory setting. All subjects contributed a urine sample prior to the session. Compared with non-drug control cues, the cocaine stimuli produced increases in physiological arousal, self-reports of high, craving, and withdrawal, and self-reports of negative mood. Subjects who tested cocaine...
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BACKGROUND Infectious diseases are the most common and cost-intensive health complications associated with drug addiction. There is wide belief that drug-dependent individuals expose themselves more regularly to disease-related pathogens through risky behaviors such as sharing pipes and needles, thereby increasing their risk for contracting an infectious disease. However, evidence is emerging i...
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After two decades of epidemic cocaine use and extensive animal research, what is known about the effects of prolonged exposure to cocaine on the central nervous system (CNS) comes from human findings. Reports of neurological and cerebrovascular infarcts attributed to cocaine abuse and studies investigating CNS function of abstinent cocaine-dependent patients provide important insights into prol...
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Introduction: A fixed hemodynamic response function (HRF) is commonly used for functional magnetic resonance imaging (fMRI) analysis. However, HRF may vary from region to region and subject to subject. We investigated the effect of locally estimated HRF (in functionally homogenous parcels) on activation detection sensitivity in a heroin cue reactivity study. Methods: We proposed...
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ژورنال
عنوان ژورنال: Psychopharmacology
سال: 2014
ISSN: 0033-3158,1432-2072
DOI: 10.1007/s00213-014-3555-9